产品名称
FADS3 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/3995
Human Swissprot No.
Q9Y5Q0
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Y5Q0/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/60527
Mouse Swissprot No.
Q9JJE7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9JJE7
Rat Gene Link
https://www.uniprot.org/uniprot/286922
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q8K1P9
免疫原
Synthesized peptide derived from human FADS3 AA range: 60-110
特异性
This antibody detects endogenous levels of FADS3 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization. [provided by RefSeq, Jul 2008],
组织表达
Highly expressed in various organs and tissues including liver, kidney, brain, lung, pancreas, testis, ovary and skeletal muscle (at protein level).
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
功能
domain:The histidine box domains may contain the active site and/or be involved in metal ion binding.,similarity:Belongs to the fatty acid desaturase family.,similarity:Contains 1 cytochrome b5 heme-binding domain.,tissue specificity:Has been found in heart, liver, lung, uterus, and brainstem.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
