产品名称
EI24 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/9538
Human Swissprot No.
O14681
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O14681/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/13663
Mouse Swissprot No.
Q61070
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q61070
Rat Gene Link
https://www.uniprot.org/uniprot/300514
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q4KM77
免疫原
Synthesized peptide derived from human EI24 AA range: 107-157
特异性
This antibody detects endogenous levels of EI24 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a putative tumor suppressor and has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The encoded protein may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 1, 3, 7, and 8. [provided by RefSeq, Feb 2014],
细胞定位
Nucleus membrane ; Multi-pass membrane protein . Cytoplasm . Endoplasmic reticulum membrane ; Multi-pass membrane protein .
功能
induction:By TP53/p53.,similarity:Belongs to the EI24 family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
