产品名称
ID1 Rabbit Polyclonal Antibody
蛋白名称
DNA-binding protein inhibitor ID-1 (Class B basic helix-loop-helix protein 24) (bHLHb24) (Inhibitor of DNA binding 1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P41134
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P41134/entry
Mouse Swissprot No.
P20067
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P20067
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P41135
免疫原
Synthesized peptide derived from human protein . at AA range: 30-110
特异性
ID1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. The encoded protein has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts. This protein may play a role in cell growth, senescence, and differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
组织表达
Lung,Ovary,Placenta,Skin,
细胞定位
Cytoplasm . Nucleus.
功能
alternative products:Additional isoforms seem to exist,developmental stage:Expression correlates with proliferation in some types of cells.,function:ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Heterodimer with other HLH proteins. Interacts with COPS5.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
