BD-PT6805

CRNL1 Rabbit Polyclonal Antibody

常规抗体

CRNKL1 CRN CGI-201 MSTP021

CRNL1

WB

Human,Mouse,Rat

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

51340

https://www.uniprot.org/uniprot/51340

Q9BZJ0

https://www.uniprot.org/uniprotkb/Q9BZJ0/entry

66877

https://www.uniprot.org/uniprot/66877

P63154

https://www.uniprot.org/uniprotkb/P63154

100910202

https://www.uniprot.org/uniprot/100910202

P63155

https://www.uniprot.org/uniprotkb/P63155

Synthesized peptide derived from human CRNL1 AA range: 710-760

This antibody detects endogenous levels of CRNL1 at Human/Mouse/Rat

WB 1：500-2000

93kD

-20°C/1 year

Polyclonal, Rabbit,IgG

The crooked neck (crn) gene of Drosophila is essential for embryogenesis and is thought to be involved in cell cycle progression and pre-mRNA splicing. A protein encoded by this human locus has been found to localize to pre-mRNA splicing complexes in the nucleus and is necessary for pre-mRNA splicing. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2013],

Widely expressed (PubMed:11342225). Highly expressed in testis (PubMed:12084575). Not detected in brain and lung (PubMed:12084575).

Nucleus . Nucleus speckle . Colocalizes with core spliceosomal snRNP proteins (PubMed:12084575). .

function:Involved in pre-mRNA splicing process.,similarity:Belongs to the crooked-neck family.,similarity:Contains 17 HAT repeats.,subcellular location:Colocalizes with core spliceosomal snRNP proteins. Also diffusely expressed in cytoplasm.,subunit:Identified in the spliceosome C complex, at least composed of AQR, C19orf29, CDC40, CDC5L, CRNKL1, DDX23, DDX41, DDX48, DDX5, DGCR14, DHX35, DHX38, DHX8, EFTUD2, FRG1, GPATC1, HNRPA1, HNRPA2B1, HNRPA3, HNRPC, HNRPF, HNRPH1, HNRPK, HNRPM, HNRPR, HNRPU, KIAA1160, KIAA1604, LSM2, LSM3, MAGOH, MORG1, PABPC1, PLRG1, PNN, PPIE, PPIL1, PPIL3, PPWD1, PRPF19, PRPF4B, PRPF6, PRPF8, RALY, RBM22, RBM8A, RBMX, SART1, SF3A1, SF3A2, SF3A3, SF3B1, SF3B2, SF3B3, SFRS1, SKIV2L2, SNRNP200, SNRNP40, SNRPA1, SNRPB, SNRPB2, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF, SNRPG, SNW1, SRRM1, SRRM2, SYF2, SYNCRIP, TFIP11, THOC4, U2AF1, XAB2 and ZCCHC8. Present in a spliceosome complex assembled in vitro containing CRNKL1, HPRP8BP and SNRPB2. Isoform 2 seems to be predominant in the spliceosome complex.,tissue specificity:Widely expressed. Highly expressed in testis. Not expressed in brain and lung.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.