产品名称
PLD6 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/201164
Human Swissprot No.
Q8N2A8
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8N2A8/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/194908
Mouse Swissprot No.
Q5SWZ9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q5SWZ9
免疫原
Synthesized peptide derived from human PLD6 AA range: 29-79
特异性
This antibody detects endogenous levels of PLD6 at Human/Mouse
稀释度
WB 1:500-2000;IHC-p 1:50-300
宿主
Polyclonal, Rabbit,IgG
组织表达
Predominantly expressed in testis and ovary, but not limited to gonads (at protein level) (PubMed:17028579, PubMed:21397847). It is also found in brain, heart, pituitary gland, prostate, pancreas, thyroid, bone marrow, lung and muscle (PubMed:21397847).
细胞定位
Mitochondrion outer membrane ; Single-pass membrane protein . Golgi apparatus . Localization in the mitochondrial outer membrane is found in different cell types where phospholipase is the predominant activity, however, in pachytene spermatocytes and spermatids of mouse testes where nuclease activity is predominant, localization is restricted to the Golgi, suggesting this enzyme is localized in different subcellular compartments depending on the role (phospholipase or nuclease) it needs to play in each cell type and developmental stage. .
功能
catalytic activity:A phosphatidylcholine + H(2)O = choline + a phosphatidate.,similarity:Belongs to the phospholipase D family.,similarity:Contains 1 PLD phosphodiesterase domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
