产品名称
KCTD3 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/51133
Human Swissprot No.
Q9Y597
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Y597/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/226823
Mouse Swissprot No.
Q8BFX3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BFX3
免疫原
Synthesized peptide derived from human KCTD3 AA range: 360-410
特异性
This antibody detects endogenous levels of KCTD3 at Human/Mouse
稀释度
WB 1:500-2000;IHC-p 1:50-300
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the potassium channel tetramerization-domain containing (KCTD) protein family. Members of this protein family regulate the biophysical characteristics of ion channels. In mouse, this protein interacts with hyperpolarization-activated cyclic nucleotide-gated channel complex 3 and enhances its cell surface expression and current density. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],
组织表达
Broadly expressed in normal tissues.
功能
miscellaneous:Reacts with sera from 5-25 per cent of cancer patients but not with sera from normal donors. Seventy per cent of renal cancer patients have antibodies against one or a panel of these antigens.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the KCTD3 family.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 5 WD repeats.,tissue specificity:Broadly expressed in normal tissues.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.