产品名称
ADAT1 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/23536
Human Swissprot No.
Q9BUB4
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9BUB4/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/30947
Mouse Swissprot No.
Q9JHI2
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9JHI2
免疫原
Synthesized peptide derived from human ADAT1 AA range: 322-372
特异性
This antibody detects endogenous levels of ADAT1 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is a member of the ADAR (adenosine deaminase acting on RNA) family. Using site-specific adenosine modification, proteins encoded by these genes participate in the pre-mRNA editing of nuclear transcripts. The protein encoded by this gene, tRNA-specific adenosine deaminase 1, is responsible for the deamination of adenosine 37 to inosine in eukaryotic tRNA. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010],
组织表达
Ubiquitously expressed.
功能
cofactor:Binds 1 inositol hexakisphosphate (IP6) per subunit.,function:Specifically deaminates adenosine-37 to inosine in tRNA-Ala.,similarity:Belongs to the ADAT1 family.,similarity:Contains 1 A to I editase domain.,tissue specificity:Ubiquitously expressed.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
