BD-PN0089

NR2C1 Rabbit Polyclonal Antibody

常规抗体

NR2C1 TR2

Nuclear receptor subfamily 2 group C member 1 (Orphan nuclear receptor TR2) (Testicular receptor 2)

WB

Human,Mouse,Rat

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.

7181

P13056

https://www.uniprot.org/uniprotkb/P13056/entry

Q505F1

http://www.uniprot.org/uniprot/Q505F1

Q8VIJ4

http://www.uniprot.org/uniprot/O54941Q8VIJ4

Synthesized peptide derived from human protein . at AA range: 40-120

NR2C1 Polyclonal Antibody detects endogenous levels of protein.

WB 1:500-2000 ELISA 1:5000-20000

66kD

-20°C/1 year

Polyclonal, Rabbit,IgG

This gene encodes a nuclear hormone receptor characterized by a highly conserved DNA binding domain (DBD), a variable hinge region, and a carboxy-terminal ligand binding domain (LBD) that is typical for all members of the steroid/thyroid hormone receptor superfamily. This protein also belongs to a large family of ligand-inducible transcription factors that regulate gene expression by binding to specific DNA sequences within promoters of target genes. Multiple alternatively spliced transcript variants have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008],

Colon,Tongue,

Nucleus . Nucleus, PML body . Recruited by HDAC3, after all-trans retinoic acid stimulated MAPK1-mediated Thr-223 phosphorylation, to PML bodies for subsequent sumoylation. .

function:Orphan nuclear receptor. Represses transcription and binds DNA as a homodimer. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism.,similarity:Belongs to the nuclear hormone receptor family. NR2 subfamily.,similarity:Contains 1 nuclear receptor DNA-binding domain.,subunit:Homodimer. Interacts with NRIP1. Directly interacts with HDAC3 and HDAC4 via the DNA-binding domain.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.