产品名称
DPEP2 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/64174
Human Swissprot No.
Q9H4A9
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9H4A9/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/319446
Mouse Swissprot No.
Q8C255
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8C255
Rat Gene Link
https://www.uniprot.org/uniprot/291984
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5M872
免疫原
Synthesized peptide derived from human DPEP2 AA range: 94-144
特异性
This antibody detects endogenous levels of DPEP2 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
DPEP2 belongs to the membrane-bound dipeptidase (EC 3.4.13.19) family. These enzymes hydrolyze a variety of dipeptides, including leukotriene D4, the beta-lactam ring of some antibiotics, and cystinyl-bis-glycine (cys-bis-gly) formed during glutathione degradation (Habib et al., 2003 [PubMed 12738806]).[supplied by OMIM, Mar 2008],
细胞定位
Membrane ; Lipid-anchor, GPI-anchor .
功能
catalytic activity:Hydrolysis of dipeptides.,cofactor:Zinc.,enzyme regulation:Inhibited by L-penicillamine.,function:Probable metalloprotease which hydrolyzes leukotriene D4 (LTD4) into leukotriene E4 (LTE4).,similarity:Belongs to the peptidase M19 family.,subunit:Homodimer; disulfide-linked.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.