产品名称
VAPA Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/9218
Human Swissprot No.
Q9P0L0
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9P0L0/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/30960
Mouse Swissprot No.
Q9WV55
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9WV55
Rat Gene Link
https://www.uniprot.org/uniprot/58857
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Z270
免疫原
Synthesized peptide derived from human VAPA AA range: 34-84
特异性
This antibody detects endogenous levels of VAPA at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a type IV membrane protein. It is present in the plasma membrane and intracellular vesicles. It may also be associated with the cytoskeleton. This protein may function in vesicle trafficking, membrane fusion, protein complex assembly and cell motility. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008],
细胞定位
Endoplasmic reticulum membrane ; Single-pass type IV membrane protein . Cell membrane ; Single-pass type IV membrane protein . Cell junction, tight junction . Nucleus membrane . Present in the plasma membrane and in intracellular vesicles, together with SNARE proteins. May also associate with the cytoskeleton. Colocalizes with OCLN at the tight junction in polarized epithelial cells. .
功能
function:May play a role in vesicle trafficking.,similarity:Contains 1 MSP domain.,subcellular location:Present in the plasma membrane and in intracellular vesicles, together with SNARE proteins. May also associate with the cytoskeleton. Colocalizes with OCLN at the tight junction in polarized epithelial cells.,subunit:Homodimer, and heterodimer with VAPB. Interacts with VAMP1, VAMP2, STX1A, BET1, SEC22C and with the C-terminal domain of OCLN. Interacts with OSBPL1A.,tissue specificity:Ubiquitous.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
