产品名称
TRI69 Rabbit Polyclonal Antibody
基因名称
TRIM69 RNF36 HSD-34 HSD34
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/140691
Human Swissprot No.
Q86WT6
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q86WT6/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/70928
Mouse Swissprot No.
Q80X56
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q80X56
Rat Gene Link
https://www.uniprot.org/uniprot/311373
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5BK82
免疫原
Synthesized peptide derived from human TRI69 AA range: 202-252
特异性
This antibody detects endogenous levels of TRI69 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the RING-B-box-coiled-coil (RBCC) family and encodes a protein with an N-terminal RING finger motif, a PRY domain and a C-terminal SPRY domain. The mouse ortholog of this gene is specifically expressed in germ cells at the round spermatid stages during spermatogenesis and, when overexpressed, induces apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Nucleus . Nucleus speckle .
功能
function:May play a role in apoptosis.,PTM:Phosphorylated. Phosphorylation is necessary for nuclear localization.,similarity:Belongs to the TRIM/RBCC family.,similarity:Contains 1 B30.2/SPRY domain.,similarity:Contains 1 RING-type zinc finger.,subunit:Interacts with PML.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
