产品名称
S38A8 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/146167
Human Swissprot No.
A6NNN8
Human Swissprot Link
https://www.uniprot.org/uniprotkb/A6NNN8/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/234788
Mouse Swissprot No.
Q5HZH7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q5HZH7
免疫原
Synthesized peptide derived from human S38A8 AA range: 191-241
特异性
This antibody detects endogenous levels of S38A8 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a putative sodium-dependent amino-acid/proton antiporter. The protein has eleven transmembrane domains, an extracellular N-terminus and an intracellular C-terminal tail. The protein is a member of the SLC38 sodium-coupled neutral amino acid transporter family of proteins. Mutations in this gene result in foveal hypoplasia with or without optic nerve misrouting and/or anterior segment dysgenesis. [provided by RefSeq, May 2014],
组织表达
Expressed in fetal and adult brain, and spinal cord. In the brain, it is localized in the cell body and axon of the majority of neuronal cells and in a subset of glial cells. Found throughout the neuronal retina, with higher expression levels in the inner and outer plexiform layers and the photoreceptor layer. Very weak expression is also present in the kidneys, thymus, and testes.
细胞定位
Membrane ; Multi-pass membrane protein .
功能
function:Putative sodium-dependent amino acid/proton antiporter.,similarity:Belongs to the amino acid/polyamine transporter 2 family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
