产品名称
DDAH1 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/23576
Human Swissprot No.
O94760
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O94760/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/69219
Mouse Swissprot No.
Q9CWS0
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9CWS0
Rat Gene Link
https://www.uniprot.org/uniprot/64157
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/O08557
免疫原
Synthesized peptide derived from human DDAH1 AA range: 115-165
特异性
This antibody detects endogenous levels of DDAH1 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. [provided by RefSeq, Jul 2008],
组织表达
Detected in brain, liver, kidney and pancreas, and at low levels in skeletal muscle.
细胞定位
mitochondrion,cytosol,extracellular exosome,
功能
catalytic activity:N(omega),N(omega)-dimethyl-L-arginine + H(2)O = dimethylamine + L-citrulline.,cofactor:Binds 1 zinc ion.,function:Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in nitric oxide generation.,similarity:Belongs to the DDAH family.,subunit:Monomer.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
