产品名称
SDC3 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/9672
Human Swissprot No.
O75056
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O75056/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/20970
Mouse Swissprot No.
Q64519
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q64519
Rat Gene Link
https://www.uniprot.org/uniprot/116673
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P33671
免疫原
Synthesized peptide derived from human SDC3 AA range: 131-181
特异性
This antibody detects endogenous levels of SDC3 at Human/Mouse/Rat
稀释度
WB 1:500-2000;IHC-p 1:50-300
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene belongs to the syndecan proteoglycan family. It may play a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism. Allelic variants of this gene have been associated with obesity. [provided by RefSeq, Oct 2009],
组织表达
Expressed in the nervous system, the adrenal gland, and the spleen.
细胞定位
Cell membrane; Single-pass type I membrane protein.
功能
function:Cell surface proteoglycan that may bear heparan sulfate (By similarity). May have a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism.,PTM:O-glycosylated within the Thr/Ser-rich region which could interact with lectin domains on other molecules.,similarity:Belongs to the syndecan proteoglycan family.,tissue specificity:Expressed in the nervous system, the adrenal gland, and the spleen.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.