产品名称
FNDC1 Rabbit Polyclonal Antibody
基因名称
FNDC1 FNDC2 KIAA1866 MEL4B3
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/84624
Human Swissprot No.
Q4ZHG4
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q4ZHG4/entry
Rat Gene Link
https://www.uniprot.org/uniprot/308099
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q2Q0I9
免疫原
Synthesized peptide derived from human FNDC1 AA range: 988-1038
特异性
This antibody detects endogenous levels of FNDC1 at Human/Rat
宿主
Polyclonal, Rabbit,IgG
组织表达
Almost absent from healthy skin; especially in epidermal keratinocytes, skin fibroblasts or endothelial cells and is barely detectable in benign melanocytic naevi. Expressed in the stroma close to skin tumors, in the tumor cells themselves and in the epidermis of psoriasis.
功能
caution:It is uncertain whether Met-1 or Met-53 is the initiator.,function:May be an activator of G protein signaling.,induction:By TGF-beta present in the melanoma cell conditioned medium (MCCM).,similarity:Contains 5 fibronectin type-III domains.,tissue specificity:Almost absent from healthy skin; especially in epidermal keratinocytes, skin fibroblasts or endothelial cells and is barely detectable in benign melanocytic naevi. Expressed in the stroma close to skin tumors, in the tumor cells themselves and in the epidermis of psoriasis.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.