产品名称
BT3A3 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/10384
Human Swissprot No.
O00478
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O00478/entry
免疫原
Synthesized peptide derived from human BT3A3 AA range: 148-198
特异性
This antibody detects endogenous levels of BT3A3 at Human
宿主
Polyclonal, Rabbit,IgG
背景介绍
The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A3) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]).[supplied by OMIM, Nov 2010],
组织表达
Detected in peripheral blood mononuclear cells and in T-cells (at protein level). Detected in spleen and lymphocytes.
细胞定位
Cell membrane ; Single-pass type I membrane protein .
功能
similarity:Belongs to the immunoglobulin superfamily. BTN/MOG family.,similarity:Contains 1 B30.2/SPRY domain.,similarity:Contains 2 Ig-like V-type (immunoglobulin-like) domains.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
