产品名称
NAT8L Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/339983
Human Swissprot No.
Q8N9F0
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8N9F0/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/269642
Mouse Swissprot No.
Q3UGX3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q3UGX3
Rat Gene Link
https://www.uniprot.org/uniprot/289727
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/D3ZVU9
免疫原
Synthesized peptide derived from human NAT8L AA range: 218-268
特异性
This antibody detects endogenous levels of NAT8L at Human/Mouse/Rat
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a single-pass membrane protein, which contains a conserved sequence of the GCN5 or NAT superfamily of N-acetyltransferases and is a member of the N-acyltransferase (NAT) superfamily. This protein is a neuron-specific protein and is the N-acetylaspartate (NAA) biosynthetic enzyme, catalyzing the NAA synthesis from L-aspartate and acetyl-CoA. NAA is a major storage and transport form of acetyl coenzyme A specific to the nervous system. The gene mutation results in primary NAA deficiency (hypoacetylaspartia). [provided by RefSeq, Dec 2010],
细胞定位
Cytoplasm . Microsome membrane ; Single-pass membrane protein . Mitochondrion membrane ; Single-pass membrane protein . Endoplasmic reticulum membrane ; Single-pass membrane protein . Its enzymatic activity contribution is quantitatively larger in mitochondrial compartment than in extramitochondrial compartment. .
功能
similarity:Belongs to the camello family.,similarity:Contains 1 N-acetyltransferase domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
