产品名称
NDK7 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/29922
Human Swissprot No.
Q9Y5B8
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Y5B8/entry
Mouse Swissprot No.
Q9QXL8
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9QXL8
Rat Gene Link
https://www.uniprot.org/uniprot/171566
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q9QXL7
免疫原
Synthesized peptide derived from human NDK7 AA range: 152-202
特异性
This antibody detects endogenous levels of NDK7 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the non-metastatic expressed family of nucleoside diphosphate kinases. Members of this family are enzymes that catalyzes phosphate transfer from nucleoside triphosphates to nucleoside diphosphates. This protein contains two kinase domains, one of which is involved in autophosphorylation and the other may be inactive. This protein localizes to the centrosome and functions as a component of the gamma-tubulin ring complex which plays a role in microtubule organization. Mutations in this gene may be associated with venous thromboembolism. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016],
功能
catalytic activity:ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.,cofactor:Magnesium.,function:Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.,similarity:Belongs to the NDK family.,similarity:Contains 1 DM10 domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
