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ITM2C Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT6651
产品名称
ITM2C Rabbit Polyclonal Antibody
类别
常规抗体
基因名称
ITM2C BRI3 hucep-14 NPD018 PSEC0047
蛋白名称
ITM2C
推荐应用
WB
反应种属
Human,Mouse,Rat
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
81618
Human Gene Link
https://www.uniprot.org/uniprot/81618
Human Swissprot No.
Q9NQX7
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NQX7/entry
Mouse Gene ID
64294
Mouse Gene Link
https://www.uniprot.org/uniprot/64294
Mouse Swissprot No.
Q91VK4
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q91VK4
Rat Gene ID
301575
Rat Gene Link
https://www.uniprot.org/uniprot/301575
Rat Swissprot No.
Q5PQL7
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5PQL7
免疫原
Synthesized peptide derived from human ITM2C AA range: 1-51
特异性
This antibody detects endogenous levels of ITM2C at Human/Mouse/Rat
稀释度
WB 1:500-2000;IHC-p 1:50-300
参考分子量
29kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
组织表达
High levels in the brain, specifically in the cerebral cortex, medulla, amygdala, hippocampus, thalamus, caudate nucleus, cerebellum, olfactory lobe and spinal cord. Very low levels in other organs.
细胞定位
Lysosome membrane ; Single-pass type II membrane protein . Cell membrane ; Single-pass type II membrane protein .
功能
PTM:Type I membrane-bound, as well as soluble, furin has a pre-eminent role in ITM2C proteolytic processing. PCSK7 and PCSK5 may also be involved although to a lesser extent. The soluble form of PCSK7 is incapable of processing ITM2C.,similarity:Belongs to the ITM2 family.,similarity:Contains 1 BRICHOS domain.,subunit:Interacts with BACE1.,tissue specificity:High levels in the brain, specifically in the cerebral cortex, medulla, amygdala, hippocampus, thalamus, caudate nucleus, cerebellum, olfactory lobe and spinal cord. Very low levels in other organs.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

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