产品名称
FDFT Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/2222
Human Swissprot No.
P37268
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P37268/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/14137
Mouse Swissprot No.
P53798
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P53798
Rat Gene Link
https://www.uniprot.org/uniprot/29580
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q02769
免疫原
Synthesized peptide derived from human FDFT AA range: 11-61
特异性
This antibody detects endogenous levels of FDFT at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq, Jul 2008],
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
功能
catalytic activity:2 farnesyl diphosphate = diphosphate + presqualene diphosphate.,catalytic activity:Presqualene diphosphate + NAD(P)H = squalene + diphosphate + NAD(P)(+).,cofactor:Magnesium.,pathway:Terpene metabolism; lanosterol biosynthesis; lanosterol from farnesyl-PP: step 1/3.,similarity:Belongs to the phytoene/squalene synthetase family.,subunit:Monomer.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
