产品名称
CETN1 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/1068
Human Swissprot No.
Q12798
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q12798/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/26369
Mouse Swissprot No.
P41209
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P41209
免疫原
Synthesized peptide derived from human CETN1 AA range: 96-146
特异性
This antibody detects endogenous levels of CETN1 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene plays important roles in the determination of centrosome position and segregation, and in the process of microtubule severing. This protein is localized to the centrosome of interphase cells, and redistributes to the region of the spindle poles during mitosis, reflecting the dynamic behavior of the centrosome during the cell cycle. [provided by RefSeq, Jan 2015],
细胞定位
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cell projection, cilium . Centrosome of interphase and mitotic cells. In the retinal photoreceptor cells, localizes at the connecting cilium, a thin bridge linking the cell body and the light-sensing outer segment (By similarity). .
功能
function:Plays a fundamental role in microtubule-organizing center structure and function.,miscellaneous:Binds two moles of calcium per mole of protein.,similarity:Belongs to the centrin family.,similarity:Contains 4 EF-hand domains.,subcellular location:Centrosome of interphase and mitotic cells.,subunit:Monomer.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
