产品名称
CHD1 Rabbit Polyclonal Antibody
蛋白名称
Chromodomain-helicase-DNA-binding protein 1 (CHD-1) (EC 3.6.4.12) (ATP-dependent helicase CHD1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
O14646
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O14646/entry
Mouse Swissprot No.
P40201
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P40201
免疫原
Synthesized peptide derived from human protein . at AA range: 960-1040
特异性
CHD1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. [provided by RefSeq, Jul 2008],
组织表达
Expressed in many tissues including in the brain, where the highest level of expression is found in the cerebellum and basal ganglia.
细胞定位
Nucleus . Cytoplasm . Is released into the cytoplasm when cells enter mitosis and is reincorporated into chromatin during telophase-cytokinesis. .
功能
function:Sequence-selective DNA-binding protein. Could play an important role in gene regulation.,similarity:Belongs to the SNF2/RAD54 helicase family.,similarity:Contains 1 helicase ATP-binding domain.,similarity:Contains 1 helicase C-terminal domain.,similarity:Contains 2 chromo domains.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
