产品名称
TRI66 Rabbit Polyclonal Antibody
基因名称
TRIM66 C11orf29 KIAA0298
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/9866
Human Swissprot No.
O15016
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O15016/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/330627
Mouse Swissprot No.
Q924W6
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q924W6
免疫原
Synthesized peptide derived from human TRI66 AA range: 608-658
特异性
This antibody detects endogenous levels of TRI66 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
细胞定位
Nucleus. Forms discrete foci within the centromeric chromocenter and surrounding nucleoplasm. .
功能
function:May function as transcription repressor; The repressive effects are mediated, at least in part, by recruitment of deacetylase activity. May play a role as negative regulator of postmeiotic genes acting through CBX3 complex formation and centromere association.,similarity:Contains 1 bromo domain.,similarity:Contains 1 PHD-type zinc finger.,similarity:Contains 2 B box-type zinc fingers.,subcellular location:Forms discrete foci within the centromeric chromocenter and surrounding nucleoplasm.,subunit:Can form homo- and heterodimers. Interacts with CBX5, CBX1 and CBX3 via PxVxL motif.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
