产品名称
AK1BA Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/57016
Human Swissprot No.
O60218
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O60218/entry
免疫原
Synthesized peptide derived from human AK1BA AA range: 124-174
特异性
This antibody detects endogenous levels of AK1BA at Human
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis. [provided by RefSeq, Jul 2008],
组织表达
Found in many tissues. Highly expressed in small intestine, colon and adrenal gland.
细胞定位
Lysosome . Secreted . Secreted through a lysosome-mediated non-classical pathway.
功能
enzyme regulation:Inhibited by tolrestat.,function:Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs.,similarity:Belongs to the aldo/keto reductase family.,tissue specificity:Found in many tissues. Highly expressed in small intestine, colon and adrenal gland.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
