产品名称
BAZ1A Rabbit Polyclonal Antibody
基因名称
BAZ1A ACF1 WCRF180 HSPC317
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/11177
Human Swissprot No.
Q9NRL2
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NRL2/entry
Mouse Swissprot No.
O88379
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/O88379
免疫原
Synthesized peptide derived from human BAZ1A AA range: 736-786
特异性
This antibody detects endogenous levels of BAZ1A at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
The BAZ1A gene encodes the accessory subunit of the ATP-dependent chromatin assembly factor (ACF), a member of the ISWI ('imitation switch') family of chromatin remodeling complexes (summarized by Racki et al., 2009 [PubMed 20033039]).[supplied by OMIM, Apr 2010],
组织表达
Highly expressed in testis and at low or undetectable levels in other tissues analyzed.
细胞定位
Nucleus. May target the CHRAC complex to heterochromatin.
功能
function:May play a role in transcriptional regulation. May be involved in the formation or maintenance of heterochromatin playing a critical role in developmental control.,miscellaneous:Stimulated by double-stranded DNA and nucleosomal DNA.,similarity:Belongs to the WAL family.,similarity:Contains 1 bromo domain.,similarity:Contains 1 DDT domain.,similarity:Contains 1 PHD-type zinc finger.,similarity:Contains 1 WAC domain.,subcellular location:May target the CHRAC complex to heterochromatin.,subunit:Together with CHRAC1, POLE3 and SMARCA5 proteins, it forms the ISWI chromatin-remodeling complex, CHRAC.,tissue specificity:Highly expressed in testis and at low or undetectable levels in other tissues analyzed.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
