产品名称
GCM1 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/8521
Human Swissprot No.
Q9NP62
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NP62/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/14531
Mouse Swissprot No.
P70348
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P70348
Rat Gene Link
https://www.uniprot.org/uniprot/29394
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Z288
免疫原
Synthesized peptide derived from human GCM1 AA range: 298-348
特异性
This antibody detects endogenous levels of GCM1 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a DNA-binding protein with a gcm-motif (glial cell missing motif). The encoded protein is a homolog of the Drosophila glial cells missing gene (gcm). This protein binds to the GCM-motif (A/G)CCCGCAT, a novel sequence among known targets of DNA-binding proteins. The N-terminal DNA-binding domain confers the unique DNA-binding activity of this protein. [provided by RefSeq, Jul 2008],
组织表达
Highly expressed in the placenta (PubMed:10542267). Expressed in trophoblast cells of the villi (PubMed:27917469).
功能
function:Transcription factor that is necessary for placental development. Binds to the trophoblast-specific element 2 (TSE2) of the aromatase gene enhancer.,similarity:Contains 1 GCM DNA-binding domain.,tissue specificity:Placenta specific.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
