产品名称
ZBED6 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/100381270
Human Swissprot No.
P86452
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P86452/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/667118
Mouse Swissprot No.
D2EAC2
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/D2EAC2
免疫原
Synthesized peptide derived from human ZBED6 AA range :130-190
特异性
This antibody detects endogenous levels of ZBED6 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this transposon-derived intronless gene is a transcriptional repressor that binds to the consensus sequence 5'-GCTCGC-3'. The encoded protein has been shown to repress IGF2 transcription. This gene is located within the first intron of the ZC3H11A gene. [provided by RefSeq, Jul 2016],
组织表达
Expressed in pancreatic islet cells (at protein level).
细胞定位
Nucleus . Nucleus, nucleolus . Cytoplasm . Located predominantly in the nucleolus but is also dispersed throughout the nucleus (By similarity). Mainly cytoplasmic in insulin- and glucagon-positive islet pancreatic cells, however nuclear localization is evidence in some pancreatic endocrine cells (PubMed:24043816). .
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
