产品名称
RRAS Rabbit Polyclonal Antibody
蛋白名称
Ras-related protein R-Ras (p23)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P10301
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P10301/entry
Mouse Swissprot No.
P10833
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P10833
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941D3Z8L7
免疫原
Synthesized peptide derived from human protein . at AA range: 1-80
特异性
RRAS Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a small GTPase involved in diverse processes including angiogenesis, vascular homeostasis and regeneration, cell adhesion, and neuronal axon guidance. Mutations in this gene are found in many invasive cancers. [provided by RefSeq, Jul 2015],
组织表达
Adipocyte,Brain,Uterus,
细胞定位
Cell membrane ; Lipid-anchor ; Cytoplasmic side . Inner surface of plasma membrane possibly with attachment requiring acylation of the C-terminal cysteine (By similarity with RAS).
信号通路
MAPK_ERK_Growth;MAPK_G_Protein;Tight junction;Regulates Actin and Cytoskeleton;
功能
function:Regulates the organization of the actin cytoskeleton.,similarity:Belongs to the small GTPase superfamily. Ras family.,subcellular location:Inner surface of plasma membrane possibly with attachment requiring acylation of the C-terminal cysteine (By similarity with RAS).,subunit:Interacts with PLCE1.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.