产品名称
PEF1 Rabbit Polyclonal Antibody
基因名称
PEF1 ABP32 UNQ1845/PRO3573
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/553115
Human Swissprot No.
Q9UBV8
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9UBV8/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/67898
Mouse Swissprot No.
Q8BFY6
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BFY6
Rat Gene Link
https://www.uniprot.org/uniprot/297900
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q641Z8
免疫原
Synthesized peptide derived from human PEF1 AA range: 109-159
特异性
This antibody detects endogenous levels of PEF1 at Human/Mouse/Rat
稀释度
WB 1:500-2000;IHC-p 1:50-300
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. The encoded protein has been shown to form a heterodimer with the programmed cell death 6 gene product and may modulate its function in Ca(2+) signaling. Alternative splicing results in multiple transcript variants and a pseudogene has been identified on chromosome 1.[provided by RefSeq, May 2010],
细胞定位
Cytoplasm . Endoplasmic reticulum . Membrane ; Peripheral membrane protein . Cytoplasmic vesicle, COPII-coated vesicle membrane ; Peripheral membrane protein . Membrane-associated in the presence of Ca(2+) (PubMed:11278427). Localizes to endoplasmic reticulum exit site (ERES) (By similarity). .
功能
similarity:Contains 5 EF-hand domains.,subcellular location:Membrane-associated in the presence of Ca(2+).,subunit:Heterodimer; heterodimerizes with PDCD6/ALG2. Dissociates from PDCD6/ALG2 in presence of Ca(2+).,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
