BD-PT6545

GLDN Rabbit Polyclonal Antibody

常规抗体

GLDN COLM UNQ9339/PRO34011

GLDN

WB

Human,Mouse,Rat

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

342035

https://www.uniprot.org/uniprot/342035

Q6ZMI3

https://www.uniprot.org/uniprotkb/Q6ZMI3/entry

235379

https://www.uniprot.org/uniprot/235379

Q8BMF8

https://www.uniprot.org/uniprotkb/Q8BMF8

315675

https://www.uniprot.org/uniprot/315675

Q80WL1

https://www.uniprot.org/uniprotkb/Q80WL1

Synthesized peptide derived from human GLDN AA range: 461-511

This antibody detects endogenous levels of GLDN at Human/Mouse/Rat

WB 1：500-2000

61kD

-20°C/1 year

Polyclonal, Rabbit,IgG

Specifically expressed in spinal cord, brain, placenta and sciatic nerve. More abundant in peripheral than central nervous system.

Cell membrane ; Single-pass type II membrane protein . Cell projection, axon . Detected at the nodes of Ranvier. Detected at immature heminodes. .; [Gliomedin shedded ectodomain]: Secreted . Secreted, extracellular space, extracellular matrix . Proteolytic processing gives rise to a soluble extracellular domain that is secreted. The gliomedin shedded ectodomain localizes to the nodes of Ranvier. .

domain:The olfactomedin-like domain mediates NFASC/neurofascin and NRCAM binding.,function:Plays a role in the formation of the nodes of Ranvier along myelinated axons. Probable NRCAM and NFASC/neurofascin ligand which may provide a glial positional clue required for the proper molecular assembly of the nodes of Ranvier.,similarity:Contains 1 olfactomedin-like domain.,similarity:Contains 2 collagen-like domains.,subcellular location:Localizes to the nodes of Ranvier.,subunit:Interacts with NFASC/neurofascin and NRCAM.,tissue specificity:Specifically expressed in spinal cord, brain, placenta and sciatic nerve. More abundant in peripheral than central nervous system.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.