产品名称
ATD3A Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/55210
Human Swissprot No.
Q9NVI7
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NVI7/entry
免疫原
Synthesized peptide derived from human ATD3A AA range: 433-483
特异性
This antibody detects endogenous levels of ATD3A at Human
宿主
Polyclonal, Rabbit,IgG
背景介绍
ATAD3A and ATAD3B (MIM 612317) are mitochondrial membrane proteins that contribute to the stabilization of large mitochondrial DNA (mtDNA)-protein complexes called nucleoids (He et al., 2007 [PubMed 17210950]).[supplied by OMIM, Sep 2008],
组织表达
Overexpressed in lung adenocarcinomas (at protein level).
细胞定位
Mitochondrion inner membrane ; Single-pass membrane protein . Mitochondrion matrix, mitochondrion nucleoid . In the mitochondrial inner membrane, enriched in sites with the potential to form contacts with the outer membrane (PubMed:20349121, PubMed:20154147). The N-terminal domain interacts with the inner surface of the mitochondrial outer membrane and the C-terminal domain localizes in a specific matrix compartment, where it is associated with nucleoids (PubMed:18063578). .
功能
similarity:Belongs to the AAA ATPase family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
