产品名称
CSTF3 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/1479
Human Swissprot No.
Q12996
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q12996/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/228410
Mouse Swissprot No.
Q99LI7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q99LI7
免疫原
Synthesized peptide derived from human CSTF3 AA range: 231-281
特异性
This antibody detects endogenous levels of CSTF3 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is one of three (including CSTF1 and CSTF2) cleavage stimulation factors that combine to form the cleavage stimulation factor complex (CSTF). This complex is involved in the polyadenylation and 3' end cleavage of pre-mRNAs. The encoded protein functions as a homodimer and interacts directly with both CSTF1 and CSTF2 in the CSTF complex. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
功能
function:One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs.,similarity:Contains 9 HAT repeats.,subunit:Homodimer. The CSTF complex is composed of CSTF1 (50 kDa subunit), CSTF2 (64 kDa subunit) and CSTF3 (77 kDa subunit). CSTF3 directly interacts with CSTF1 and CSTF2. Interacts with FIP1L1.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
