产品名称
CNDH2 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/29781
Human Swissprot No.
Q6IBW4
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q6IBW4/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/52683
Mouse Swissprot No.
Q8BSP2
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BSP2
Rat Gene Link
https://www.uniprot.org/uniprot/300149
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q4V8I2
免疫原
Synthesized peptide derived from human CNDH2 AA range: 501-551
特异性
This antibody detects endogenous levels of CNDH2 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes one of the non-SMC subunits of the condensin II complex. This complex plays an essential role in mitotic chromosome assembly. Alternate splicing of this gene results in multiple transcript variants.[provided by RefSeq, May 2010],
细胞定位
Nucleus . Chromosome . Distributed along the arms of chromosomes assembled in vivo and in vitro.
功能
function:Regulatory subunit of the condensin-2 complex, a complex that seems to provide chromosomes with an additional level of organization and rigidity and in establishing mitotic chromosome architecture. May play a role in lineage-specific role in T-cell development.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the CND2 H2 (condensin-2 subunit 2) family.,subcellular location:Distributed along the arms of chromosomes assembled in vivo and in vitro.,subunit:Component of the condensin-2 complex, which contains the smc2 and smc4 heterodimer, and three non SMC subunits, ncapg2, ncaph2 and ncapd3 that probably regulate the complex.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
