产品名称
NUDT6 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/11162
Human Swissprot No.
P53370
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P53370/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/229228
Mouse Swissprot No.
Q8CH40
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8CH40
Rat Gene Link
https://www.uniprot.org/uniprot/207120
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P70563
免疫原
Synthesized peptide derived from human NUDT6 AA range: 225-275
特异性
This antibody detects endogenous levels of NUDT6 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene overlaps and lies on the opposite strand from FGF2 gene, and is thought to be the FGF2 antisense gene. The two genes are independently transcribed, and their expression shows an inverse relationship, suggesting that this antisense transcript may regulate FGF2 expression. This gene has also been shown to have hormone-regulatory and antiproliferative actions in the pituitary that are independent of FGF2 expression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],
组织表达
Detected in liver, kidney and esophagus (at protein level). Ubiquitous.
细胞定位
Cytoplasm. Nucleus. Mitochondrion. Subcellular location may vary between isoforms.
功能
miscellaneous:This protein is coded from a FGF2 (BFGF) gene antisense transcript.,similarity:Belongs to the Nudix hydrolase family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.