产品名称
CHD1 Rabbit Polyclonal Antibody
蛋白名称
Chromodomain-helicase-DNA-binding protein 1 (CHD-1) (EC 3.6.4.12) (ATP-dependent helicase CHD1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
O14646
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O14646/entry
Mouse Swissprot No.
P40201
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P40201
免疫原
Synthesized peptide derived from human protein . at AA range: 960-1040
特异性
CHD1 Polyclonal Antibody detects endogenous levels of protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. [provided by RefSeq, Jul 2008],
组织表达
Expressed in many tissues including in the brain, where the highest level of expression is found in the cerebellum and basal ganglia.
细胞定位
Nucleus . Cytoplasm . Is released into the cytoplasm when cells enter mitosis and is reincorporated into chromatin during telophase-cytokinesis. .
功能
function:Sequence-selective DNA-binding protein. Could play an important role in gene regulation.,similarity:Belongs to the SNF2/RAD54 helicase family.,similarity:Contains 1 helicase ATP-binding domain.,similarity:Contains 1 helicase C-terminal domain.,similarity:Contains 2 chromo domains.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
