产品名称
LRC3B Rabbit Polyclonal Antibody
基因名称
LRRC3B LRP15 UNQ195/PRO221
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/116135
Human Swissprot No.
Q96PB8
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q96PB8/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/218763
Mouse Swissprot No.
Q8VCH9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8VCH9
免疫原
Synthesized peptide derived from human LRC3B AA range: 115-165
特异性
This antibody detects endogenous levels of LRC3B at Human/Mouse
稀释度
WB 1:500-2000;IHC-p 1:50-300
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a tumor suppressor, with lowered expression levels found in gastric, renal, colorectal, lung, and breast cancer tissues. The promoter of this gene is frequently hypermethylated in these cancer tissues, although the hypermethylation does not appear to be the cause of the reduced expression of this gene. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2015],
细胞定位
Membrane ; Single-pass membrane protein .
功能
similarity:Belongs to the LRRC3 family.,similarity:Contains 3 LRR (leucine-rich) repeats.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
