产品名称
FBX41 Rabbit Polyclonal Antibody
基因名称
FBXO41 FBX41 KIAA1940
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/150726
Human Swissprot No.
Q8TF61
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8TF61/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/330369
Mouse Swissprot No.
Q6NS60
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q6NS60
免疫原
Synthesized peptide derived from human FBX41 AA range: 622-672
特异性
This antibody detects endogenous levels of FBX41 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the F-box protein family, which is characterized by an approximately 40 amino acid motif, the F-box. F-box proteins constitute one of the four subunits of the SCF ubiquitin protein ligase complex that plays a role in phosphorylation-dependent ubiquitination. F-box proteins are divided into three classes depending on the interaction substrate domain each contains in addition to the F-box motif: FBXW proteins contain WD-40 domains, FBXL proteins contain leucine-rich repeats, and FBXO proteins contain either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the FBXO class. [provided by RefSeq, Feb 2014],
功能
function:Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.,similarity:Contains 1 F-box domain.,subunit:Directly interacts with SKP1A and CUL1.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
