产品名称
GRPE1 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/80273
Human Swissprot No.
Q9HAV7
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9HAV7/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/17713
Mouse Swissprot No.
Q99LP6
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q99LP6
Rat Gene Link
https://www.uniprot.org/uniprot/79563
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P97576
免疫原
Synthesized peptide derived from human GRPE1 AA range: 159-209
特异性
This antibody detects endogenous levels of GRPE1 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
细胞定位
Mitochondrion matrix .
功能
function:Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins.,similarity:Belongs to the grpE family.,subunit:Probable component of the PAM complex at least composed of a mitochondrial HSP70 protein, GRPEL1 or GRPEL2, TIMM44, TIMM16/MAGMAS and TIMM14/DNAJC19 (By similarity). Binds to HSP70, HSC70 and HSJ1B.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
