产品名称
RHBT2 Rabbit Polyclonal Antibody
基因名称
RHOBTB2 DBC2 KIAA0717
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/23221
Human Swissprot No.
Q9BYZ6
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9BYZ6/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/246710
Mouse Swissprot No.
Q91V93
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q91V93
免疫原
Synthesized peptide derived from human RHBT2 AA range: 573-623
特异性
This antibody detects endogenous levels of RHBT2 at Human/Mouse
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell division. This protein inhibits the growth and spread of some types of breast cancer. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011],
组织表达
Ubiquitous, with highest levels in neural tissues. Expression is also detected in fetal lung, heart, and brain.
细胞定位
intracellular,cytosol,plasma membrane,
功能
similarity:Belongs to the small GTPase superfamily. Rho family.,similarity:Contains 2 BTB (POZ) domains.,tissue specificity:Ubiquitous, with highest levels in neural tissues. Expression is also detected in fetal lung, heart, and brain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
