产品名称
HCFC2 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/29915
Human Swissprot No.
Q9Y5Z7
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Y5Z7/entry
Mouse Swissprot No.
Q9D968
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9D968
Rat Gene Link
https://www.uniprot.org/uniprot/314704
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5RKG2
免疫原
Synthesized peptide derived from human HCFC2 AA range: 347-397
特异性
This antibody detects endogenous levels of HCFC2 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes one of two proteins which interact with VP16, a herpes simplex virus protein that initiates virus infection. Both the encoded protein and the original Herpes host cell factor interact with VP16 through a beta-propeller domain. The original Herpes host cell factor, however, is effective at initiating viral infection while the encoded protein is not. Transcripts of varying length due to alternative polyadenylation signals have been described. [provided by RefSeq, Jul 2008],
组织表达
Highly expressed in testis. Detected at lower levels in spleen, thymus, prostate, ovary, small intestine and colon.
细胞定位
Cytoplasm . Nucleus .
功能
similarity:Contains 3 fibronectin type-III domains.,similarity:Contains 4 Kelch repeats.,subunit:Binds MLL. Component of the MLL complex, at least composed of MLL, ASH2L, RBBP5, DPY30, WDR5, MEN1, HCFC1 and HCFC2.,tissue specificity:Highly expressed in testis. Detected at lower levels in spleen, thymus, prostate, ovary, small intestine and colon.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
