产品名称
TM165 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/55858
Human Swissprot No.
Q9HC07
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9HC07/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/21982
Mouse Swissprot No.
P52875
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P52875
Rat Gene Link
https://www.uniprot.org/uniprot/100911646
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q4V899
免疫原
Synthesized peptide derived from human TM165 AA range: 68-118
特异性
This antibody detects endogenous levels of TM165 at Human/Mouse/Rat
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a predicted transmembrane protein with a perinuclear Golgi-like distribution in fibroblasts. Mutations in this gene are associated with the autosomal recessive disorder congenital disorder of glycosylation, type IIk. Knockdown of this gene's expression causes decreased sialylation in HEK cells and suggests this gene plays a role in terminal Golgi glycosylation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012],
组织表达
Ubiquitously expressed.
细胞定位
Golgi apparatus membrane ; Multi-pass membrane protein . Golgi apparatus, trans-Golgi network membrane. Lysosome membrane. Early endosome membrane. Late endosome membrane.
功能
similarity:Belongs to the UPF0016 family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
