产品名称
ICT1 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/3396
Human Swissprot No.
Q14197
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q14197/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/68572
Mouse Swissprot No.
Q8R035
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8R035
免疫原
Synthesized peptide derived from human ICT1 AA range: 7-57
特异性
This antibody detects endogenous levels of ICT1 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a peptidyl-tRNA hydrolase and a vital component of the large mitochondrial ribosome. The encoded protein serves as a ribosome release factor for this ribosome, which translates mitochondrial genes. This protein may be responsible for degrading prematurely-terminated polypeptides and for reusing stalled ribosomes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014],
组织表达
Down-regulated during the in vitro differentiation of HT29-D4 colon carcinoma cells.
功能
similarity:Belongs to the prokaryotic/mitochondrial release factor family.,tissue specificity:Down-regulated during the in vitro differentiation of HT29-D4 colon carcinoma cells.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
