产品名称
LRC26 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/389816
Human Swissprot No.
Q2I0M4
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q2I0M4/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/227618
Mouse Swissprot No.
Q91W20
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q91W20
Rat Gene Link
https://www.uniprot.org/uniprot/311803
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q6P7C4
免疫原
Synthesized peptide derived from human LRC26 AA range: 163-213
特异性
This antibody detects endogenous levels of LRC26 at Human/Mouse/Rat
稀释度
WB 1:500-2000;IHC-p 1:50-300
宿主
Polyclonal, Rabbit,IgG
组织表达
Isoform 1 is expressed highly in normal prostate and salivary gland, very weakly in colon, pancreas, and intestine, and not at all in other tissues. Isoform 1 is expressed highly in many cancer cell lines and in breast cancer, pancreatic cancer and colon cancer. Isoform 2 is expressed in cancer cell lines.
细胞定位
Cell membrane; Single-pass type I membrane protein. Cytoplasm, cytoskeleton. Localizes to the cytoplasm when expressed at high levels. .
功能
similarity:Contains 6 LRR (leucine-rich) repeats.,subcellular location:Although predicted to be a single-pass type I membrane protein, this protein localizes to the cytoplasm when expressed at high levels (PubMed:15164053).,tissue specificity:Expressed highly in normal prostate and salivary gland, very weakly in colon, pancreas, and intestine, and not at all in other tissues. Expressed highly in many cancer cell lines and in breast cancer, pancreatic cancer and colon cancer.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.