产品名称
ROA0 Rabbit Polyclonal Antibody
蛋白名称
Heterogeneous nuclear ribonucleoprotein A0 (hnRNP A0)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q13151
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q13151/entry
Mouse Swissprot No.
Q9CX86
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9CX86
免疫原
Synthesized peptide derived from human protein . at AA range: 20-100
特异性
ROA0 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind RNAs, followed by a glycine-rich C-terminus. [provided by RefSeq, Jul 2008],
组织表达
Brain,Colon carcinoma,Eye,Lung,Muscle,Ovarian carcinoma,Pla
细胞定位
Nucleus . Component of ribonucleosomes. .
功能
function:This protein is a component of ribonucleosomes.,PTM:Arg-291 is dimethylated, probably to asymmetric dimethylarginine.,similarity:Contains 2 RRM (RNA recognition motif) domains.,subcellular location:Component of ribonucleosomes.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.