产品名称
KDEL1 Rabbit Polyclonal Antibody
基因名称
KDELC1 EP58 UNQ1910/PRO4357
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/79070
Human Swissprot No.
Q6UW63
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q6UW63/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/72050
Mouse Swissprot No.
Q9JHP7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9JHP7
免疫原
Synthesized peptide derived from human KDEL1 AA range: 4-54
特异性
This antibody detects endogenous levels of KDEL1 at Human/Mouse
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protein product localized to the lumen of the endoplasmic reticulum. As a member of the endoplasmic reticulum protein family the encoded protein contains a Lys-Asp-Glu-Leu or KDEL motif located at the extreme C-terminus which prevents all endoplasmic reticulum resident proteins from being secreted. Proteins carrying this motif are bound by a receptor in the Golgi apparatus so that the receptor-ligand complex returns to the endoplasmic reticulum. A processed non-transcribed pseudogene located in an intron of a sodium transporter gene on chromosome 5 has been defined for this gene. This gene has multiple transcript variants which are predicted to encode distinct isoforms. [provided by RefSeq, Jan 2016],
细胞定位
Endoplasmic reticulum lumen .
功能
PTM:N-glycosylated.,similarity:Belongs to the KDELC family.,similarity:Contains 1 filamin repeat.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
