产品名称
ANXA8 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/244
Human Swissprot No.
P13928
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P13928/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/11752
Mouse Swissprot No.
O35640
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/O35640
Rat Gene Link
https://www.uniprot.org/uniprot/306283
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q4FZU6
免疫原
Synthesized peptide derived from human ANXA8 AA range: 244-294
特异性
This antibody detects endogenous levels of ANXA8 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The encoded protein may function as an an anticoagulant that indirectly inhibits the thromboplastin-specific complex. Overexpression of this gene has been associated with acute myelocytic leukemia. A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10. [provided by RefSeq, Jul 2008],
细胞定位
cytosol,plasma membrane,late endosome membrane,
功能
domain:A pair of annexin repeats may form one binding site for calcium and phospholipid.,function:This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.,similarity:Belongs to the annexin family.,similarity:Contains 4 annexin repeats.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
