产品名称
BEAN1 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/146227
Human Swissprot No.
Q3B7T3
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q3B7T3/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/65115
Mouse Swissprot No.
Q9EQG5
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9EQG5
免疫原
Synthesized peptide derived from human BEAN1 AA range: 146-196
特异性
This antibody detects endogenous levels of BEAN1 at Human/Mouse
稀释度
wb 1:1000 IP:1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is one of several proteins that interact with NEDD4, a member of a family of ubiquitin-protein ligases. These proteins have PY motifs in common that bind to the WW domains of NEDD4. NEDD4 is developmentally regulated, and is highly expressed in embryonic tissues. Mutations in this gene (i.e., intronic insertions of >100 copies of pentanucleotide repeats including a (TGGAA)n sequence) are associated with spinocerebellar ataxia type 31. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010],
细胞定位
Membrane ; Single-pass membrane protein .
功能
subunit:Interacts with NEDD4.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
