产品名称
UBP28 Rabbit Polyclonal Antibody
蛋白名称
Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.4.19.12) (Deubiquitinating enzyme 28) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q96RU2
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q96RU2/entry
Mouse Swissprot No.
Q5I043
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q5I043
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941D3ZJ96
免疫原
Synthesized peptide derived from human protein . at AA range: 650-730
特异性
UBP28 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a deubiquitinase involved in the DNA damage pathway and DNA damage-induced apoptosis. Overexpression of this gene is seen in several cancers. [provided by RefSeq, Oct 2016],
细胞定位
Nucleus, nucleoplasm .
功能
catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the peptidase C19 family.,similarity:Contains 1 UIM (ubiquitin-interacting motif) repeat.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
