产品名称
PIGL Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/9487
Human Swissprot No.
Q9Y2B2
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Y2B2/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/327942
Mouse Swissprot No.
Q5SX19
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q5SX19
Rat Gene Link
https://www.uniprot.org/uniprot/192263
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/O35790
免疫原
Synthesized peptide derived from human PIGL AA range: 77-127
特异性
This antibody detects endogenous levels of PIGL at Human/Mouse/Rat
稀释度
WB 1:500-2000; IF ICC 1:50-200;ELISA 1:2000-20000;IHC-p 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes an enzyme that catalyzes the second step of glycosylphosphatidylinositol (GPI) biosynthesis, which is the de-N-acetylation of N-acetylglucosaminylphosphatidylinositol (GlcNAc-PI). Study of a similar rat enzyme suggests that this protein localizes to the endoplasmic reticulum. [provided by RefSeq, Jul 2008],
细胞定位
Endoplasmic reticulum membrane ; Single-pass membrane protein .
功能
catalytic activity:6-(N-acetyl-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H(2)O = 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + acetate.,function:Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.,pathway:Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.,similarity:Belongs to the PIGL family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
