产品名称
DTNA Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/1837
Human Swissprot No.
Q9Y4J8
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9Y4J8
Mouse Gene Link
https://www.uniprot.org/uniprot/13527
Mouse Swissprot No.
Q9D2N4
Mouse Swissprot Link
https://www.uniprot.org/uniprot/Q9D2N4
免疫原
Synthesized peptide derived from human DTNA
特异性
This antibody detects endogenous levels of DTNA at Human/Mouse
背景介绍
The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],
纯化
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
